Search results for "Peritoneal cavity leukocyte"

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Peritoneal cavity phagocytes from the teleost sea bass express a glucocorticoid receptor (cloned and sequenced) involved in genomic modulation of the…

2005

Abstract To gain further insight into the role of cortisol in Wsh innate immune responses, we cloned and sequenced a 2592 bp cDNA from sea bass (Dicentrarchus labrax) peritoneal leukocytes (PCLs) encoding a glucocorticoid receptor (DlGR1). The deduced aminoacid sequence displayed that DlGR1 belong to a multigenic family of steroid hormone receptors, and exhibited high homology (80%) to the Burton’s mouth breeder (Haplochromis burtoni) HbGR1. The DlGR1 functional domains presented homologies with those of several vertebrate species. In situ hybridization assay revealed that DlGR1 was expressed in macrophages and neutrophils from the peritoneal cavity. Since in a previous paper, sea bass PCL …

medicine.medical_specialtyDNA ComplementaryHydrocortisonemedicine.medical_treatmentMolecular Sequence DataDicentrarchus labrax; Peritoneal cavity leukocytes; Phagocytes; Hydrocortisone; RU486; Glucocorticoid receptor; DlGR1; GR cDNA sequence; GR mRNA expressionSequence HomologyGlucocorticoid receptorBiologyDlGR1Peritoneal cavitychemistry.chemical_compoundEndocrinologyGlucocorticoid receptorReceptors GlucocorticoidInternal medicinemedicineAnimalsDicentrarchus labraxPeritoneal cavity leukocyteAmino Acid SequenceSea bassReceptorPeritoneal CavityCells CulturedRespiratory BurstPhagocytesInnate immune systemDose-Response Relationship DrugZymosanZymosanMolecular biologyRespiratory burstSteroid hormoneGR mRNA expressionmedicine.anatomical_structureEndocrinologychemistryPhagocyteLuminescent MeasurementsGR cDNA sequenceAnimal Science and ZoologyBasshormones hormone substitutes and hormone antagonistsStress PsychologicalRU486
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